Five Membered Heterocycles with Nitrogen - PYRROLE

Pyrrole is a heterocyclic aromatic organic compound, a five-membered ring with the formula C4H4NH.[1] It is a colorless volatile liquid that darkens readily upon exposure to air. Substituted derivatives are also called pyrroles, e.g., N-methylpyrrole, C4H4NCH3. Porphobilinogen, a trisubstituted pyrrole, is the biosynthetic precursor to many natural products such as heme.
Contents :-
Structure, Stability, Aromaticity, Reactivity, Acidity & Basicity of
- Pyrrole
• Reactions – With acids, bases, alkylation, Electrophilic Aromatic Substitution (EAS), carbenes, nitrenes, oxidizing and reducing agents, Diels-Alder reaction
• Synthesis – Using furan, ammonium mucate, primary amines, Knorr synthesis, Paal- Knorr synthesis, Hantzsch synthesis, Piloty-Robinson synthesis



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